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Results for "

Zebrafish embryos

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

1

Fluorescent Dye

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119896
    Clethodim

    		Others Neurological Disease
    Clethodim is a postemergence herbicide. Clethodim shows developmental toxicity and neurotoxicity in zebrafish embryos and larvae .
    Clethodim
  • HY-147372
    SJ000063181

    		TGF-beta/Smad Metabolic Disease
    SJ000063181 is a potent BMP signaling activator with an EC50 ≤1 µM. SJ000063181 can be used as chemical probes to interrogate BMP signaling due to it can penetrate zebrafish embryos .
    SJ000063181
  • HY-107399
    CD3254
    3 Publications Verification

    		 RAR/RXR Metabolic Disease Cancer
    CD3254 a potent and selective retinoid-X-receptor (RXR) agonist .
    CD3254
  • HY-D1416
    HMBR

    		Fluorescent Dye Others
    HMBR, an analog bearing an additional methyl group on the aromatic ring, is nonfluorescent by itself, but it fluoresces yellow light upon blue-light excitation when bound to Y-FAST. HMBR is nontoxic for zebrafish embryos. cell-permeant .
    HMBR
  • HY-136439
    4-Epianhydrotetracycline hydrochloride

    		Bacterial Antibiotic Apoptosis Infection
    4-Epianhydrotetracycline hydrochloride is a major intermediate product of Tetracycline (HY-A0107). 4-Epianhydrotetracycline hydrochloride shows lethal effects and induces cell apoptosis of zebrafish embryos. 4-Epianhydrotetracycline hydrochloride inhibits Shewanella, E. coli and P. aeruginosa with MIC values of 2, 1 and 64 mg/L, respectively .
    4-Epianhydrotetracycline hydrochloride
  • HY-153936
    Methyl 12-methyltridecanoate

    		Apoptosis ROS Kinase Others
    Methyl 12-methyltridecanoate ((R)-betaxolol hydrochloride) is a biosurfactant extracted from Brevibacterium casei LS14.Methyl 12-methyltridecanoate provides a novel approach for functionalizing the silver nanoparticles higher biocompatibility in vivo environmental .
    Methyl 12-methyltridecanoate
  • HY-139059
    ERD03

    		Others Neurological Disease
    ERD03 is a potent disruptor of the EXOSC3-RNA interaction, with a Kd of 17±7 μM . ERD03 induces PCH1B-like phenotype in zebrafish embryo and can be used for neurological disorder disease research .
    ERD03
  • HY-117617
    CAY10669

    		Histone Acetyltransferase Cancer
    CAY10669 (compound 6d) is an anacardic acid (HY-N2020) derivative that inhibits histone acetyltransferase PCAF with an IC50 of 662 μM . CAY10669 enhances the SAHA-induced acetylation in HEPG2 cells, exhibits cytotoxicity in zebrafish embryo, promotes transgene expression in CHO-K1 cells .
    CAY10669
  • HY-B0717
    Tocofersolan
    3 Publications Verification

    TPGS; D-α-Tocopherol polyethylene glycol 1000 succinate; Vitamin E-TPGS

    		 Others Neurological Disease Metabolic Disease
    Tocofersolan is synthetic polyethylene glycol derivative of α-tocopherol. Tocofersolan is an orally active and water-soluble analog of vitamin E. Tocofersolan can reduce neurobehavioral deficits in zebrafish embryos exposed to moderate and high concentrations of BaP during early development. Tocofersolan shows antioxidant activity. Tocofersolan can be used to provide an orally bioavailable source of vitamin E .
    Tocofersolan
  • HY-W011616
    Cardionogen 1

    CDNG1/vuc230

    		 Wnt Cardiovascular Disease Cancer
    Cardionogen 1 (CDNG1/vuc230) is a Wnt signaling pathway inhibitor that slows down Myc-induced liver tumorigenesis. Cardionogen 1 treatment of zebrafish embryos before gastrulation inhibits cardiomyocyte formation, whereas treatment during or after gastrulation induces cardiomyocyte formation. Cardionogen 1 has potential in research into cancer and cardiovascular disease .
    Cardionogen 1
  • HY-155331
    Antifungal agent 77

    		Fungal Infection
    Antifungal agent 77 (Compound 13h) is an antifungal agent. Antifungal agent 77 (500 μg/mL) also shows good insecticidal activity against Mythimna separate, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda with a death rate of 30%, 25%, 40%, and 25%. Antifungal agent 77 shows toxicity in zebrafish embryo with a LC50 of 2.43 μg/mL .
    Antifungal agent 77
  • HY-123230
    Trifloxystrobin

    CGA 279202

    		 Fungal Caspase PARP Apoptosis Infection Neurological Disease
    Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases .
    Trifloxystrobin
  • HY-147891
    Angiogenesis inhibitor 3

    		Apoptosis Cancer
    Angiogenesis inhibitor 3 (compound 8) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 3 inhibits the proliferation of HUVEC and HCT-15 cells, with IC50 values of 1.00 and 0.71 μM. Angiogenesis inhibitor 3 induces the apoptosis of HUVEC and HCT-15 cells. Angiogenesis inhibitor 3 shows anticancer activity, and suppresses the invasion of cancer cells. Angiogenesis inhibitor 3 inhibits the angiogenesis in zebrafish embryos .
    Angiogenesis inhibitor 3
  • HY-147890
    Angiogenesis inhibitor 2

    		Apoptosis Cancer
    Angiogenesis inhibitor 2 (compound 72) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 2 inhibits the proliferation of HUVEC and HCT-15 cells, with IC50 values of 1.93 and 0.21 μM. Angiogenesis inhibitor 2 induces the apoptosis of HUVEC and HCT-15 cells. Angiogenesis inhibitor 2 shows anticancer activity, and suppresses the invasion of cancer cells. Angiogenesis inhibitor 2 inhibits the angiogenesis in zebrafish embryos .
    Angiogenesis inhibitor 2
  • HY-N11526
    3-Hydroxy-2-(palmitoyloxy)propyl stearat

    		Others Inflammation/Immunology
    3-Hydroxy-2-(palmitoyloxy)propyl stearat is a non-volatile compound. 3-Hydroxy-2-(palmitoyloxy)propyl stearat can be isolated from less polar fractions of the brown macroalga Fucus virsoides J. Agardh. This part of the substance has a good ability to scavenge free radicals and has a protective effect on the oxidative stress induced by hydrogen peroxide in zebrafish embryos .
    3-Hydroxy-2-(palmitoyloxy)propyl stearat
  • HY-N10802
    6-O-Isobutyrylbritannilactone

    		ERK Akt PI3K Epigenetic Reader Domain Cancer
    6-O-Isobutyrylbritannilactone is a natural melanogenesis inhibitor. 6-O-Isobutyrylbritannilactone, a sesquiterpene, can be isolated from the flowers of Inula britannica. 6-O-Isobutyrylbritannilactone inhibits IBMX (HY-12318)-induced melanin production in B16F10 cells. 6-O-Isobutyrylbritannilactone also regulates ERK, PI3K/AKT, and CREB, shows antimelanogenic activity in zebrafish embryos models .
    6-O-Isobutyrylbritannilactone
  • HY-N12329
    Fumonisin B4

    		Others Others
    Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .
    Fumonisin B4
  • HY-12464
    Butafenacil

    WC-9717; CGA-276854

    		 Others Others
    Butafenacil (WC-9717; CGA-276854) is an herbicide that inhibits protoporphyrinogen oxidase .
    Butafenacil
  • HY-144818
    Tubulin inhibitor 23

    		Apoptosis Microtubule/Tubulin Cancer
    Tubulin inhibitor 23 is a potent Tubulin inhibitor with an IC50 of 4.8 µM. Tubulin inhibitor 23 induces cell apoptosis. Tubulin inhibitor 23 shows antiangiogenic activity in a dose-dependent manner. Tubulin inhibitor 23 has the potential for the research of leukaemia .
    Tubulin inhibitor 23

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